COMBINED NEPHROTOXICITY OF GENTAMICIN AND METHOXYFLURANE ANAESTHESIA IN MAN
نویسندگان
چکیده
منابع مشابه
Renal function and methoxyflurane anaesthesia.
~IETHOXYFLURANE IS A DIIU(; that is being used with increasing frequency and reports in the literature have suggested that it is sometimes responsible for postoperative renal dysfunction. ~-'; Thus it seemed prudent to consider the available knowledge concerning effects of methoxyflurane on the kidney, in order to decide the manner of drug usage most likely to avoid anv undesirable renal sequel...
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AFTEX~ TrraEE YEARS of ever increasing clinical use, methoxyflurane remains an effective and relatively safe anaesthetic agent worthy of great interest in practice. Its unquestionable qualities as a stable, pote~lt hypnotic and lanalgesic, capable of inducing a muscular relaxation comparable with tl~at of deep ether, nonetheless devoid of explosive and toxic hazards, ha,~e contributed to this w...
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Gentamicin is an important aminoglycoside antibiotic. However its use is limited to serious and life threatening gram negative infections, because of its high nephrotoxicity potential in patients. There are reports that safranal, the active ingredient of saffron with antioxidant properties, exerts protective effect against ischemic injuries occurred by certain nephrotoxins including gentamicin....
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Objective(s): Gentamicin is used for the treatment of Gram-negative bacterial infections. However, gentamicin administration is limited because of nephrotoxicity. The aim of the present study was to evaluate the protective effect of crocin against gentamicin-induced nephrotoxicity in rats. Materials and Methods: Thirty two male Wistar rats received gentamicin (100 mg/kg, IP), with or without c...
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ژورنال
عنوان ژورنال: British Journal of Anaesthesia
سال: 1973
ISSN: 0007-0912
DOI: 10.1093/bja/45.4.394